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Although nearly half the kids received lithium or an anticonvulsant drug to quell manic symptoms, their bipolar condition subsided no more often than that of their unmedicated peers.
Side-effects of anticonvulsant drugs are usually not serious and are reversible once the dose is reduced or the drug is discontinued.
For decades children were given long term anticonvulsant drugs to prevent the recurrence of febrile seizures.
Its safety and efficacy as an anticonvulsant drug given intramuscularly have been shown in several studies in animals and humans (adults and children).
If satisfactory control is not established within the first three to six months, another anticonvulsant drug should be added, with the eventual goal of eliminating the first agent and achieving monotherapy.
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