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This surprised the researchers, because their previous work had suggested that the intestinal enzyme catechol - O methyltransferase played a big part in digesting flavanols, and they expected to see more O methylation going on.
Similarly, the peroxidase activity was assayed from the oxidation of catechol by H 2 O 2 in presence of the extract.
So the problem was how to change this catechol without affecting the drug's ability to interact at the receptor.
Acrolein, hydroquinone, catechol , and benzo- [a] pyrene have demonstrated immunosuppressive effects in cell and animal models.
To determine this, we crossed acd5 with a well-characterized transgenic plant harboring the nahG gene, whose product metabolizes SA to the inactive catechol .
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