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The structural distortions at the site of damage are translated across the DNA double helix to the active site of human topoisomerase I.
As the replication forks progress along the template strands the newly synthesized daughter strands and parental template strands reform a DNA double helix .
Clearly, the rigidity is different for the regions consisting of one double helix or two double helices and the bends are likely to be localized at certain points within the unit.
Water is essential for the stability and function of ‘the aperiodic crystal of heredity’ the DNA double helix .
The DNA structure is a double helix looking something like a twisted ladder.
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