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In medical diagnostics, solid-phase immunoassays are used where immunoglobulins are immobilized on a substrate, which then form sandwichlike complexes with antigens.
This has important applications in protein chromatography, immunoassays for medical diagnostic tests, development of biosensors, biotechnology, and biocatalysis.
Enzyme immunoassays for detecting chlamydial antigen and direct nucleic acid probe assays are the most widely used tests and can evaluate large numbers of samples.
The use of immunoassays that detect antibodies that bind to epitopes on the bacterial surface of the homologous infecting strain is important to detect potentially protective immune responses.
Many antibodies used in diagnostic immunoassays are derived from rabbits.
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