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Platelet concentrates also have the potential to improve fracture healing and enhance osteogenesis .
Stimulation of osteogenesis leading to bone repair, as in patients with large bone defects, fracture non-unions, and incomplete allograft consolidation, is clinically desirable for early healing and restoration of function.
Although both groups exhibit very similar chondrogenic patterns of the tarsus, only the amphibian pattern is preserved through osteogenesis .
As a consequence, the mineralized septa providing the scaffold for bone deposition cannot be formed, and osteogenesis itself is severely disturbed.
Inflammation is a necessary step in the healing of normal body tissues, and osteoblasts specifically require prostaglandins for osteogenesis and differentiation.
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