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The stoichiometric ratio between DNA molecules and microspheres is kept well below one to ensure that the vast majority of microsphere tethers consist of only a single DNA molecule.
It also reacts as a stoichiometric scavenger with organophosphates, thus having the capacity to provide prophylactic protection against highly toxic chemical warfare nerve agents, such as soman and VX.
In summary, we have developed a reconstitution method that is stoichiometric , functional, and suitable for spectroscopic studies of skeletal muscle.
The concentration of actin is fixed at 11.9 M, and the amount of scruin is varied to achieve the desired stoichiometric ratio.
It should also be noted that upon further addition of either reactant beyond the stoichiometric maximum, the complexes/aggregates are brought back into solution.
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