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Human African trypanosomiasis or sleeping sickness is one of the most important but equally most neglected tropical infections.
In terms of public health and economic impact, American trypanosomiasis (Chagas' disease) is the most important parasitic infection in Latin America.
Without medical treatment, sleeping sickness - or trypanosomiasis - is always fatal.
The relentless spread of disease in central Africa contrasts with the remarkable recent success of control programmes in South American trypanosomiasis (Chagas' disease).
How people use their environments has profoundly affected diseases like malaria and trypanosomiasis .