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cowpox
vaccinia
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Smallpox vaccine contains live vaccinia virus, a milder cousin of the variola virus.
Jenner waited only four years before declaring that the vaccine that he named vaccinia provided immunity from smallpox for life.
The live vaccinia virus that is used for the smallpox vaccination is admittedly the most dangerous vaccine in use.
Then the immune-impaired and those susceptible to vaccinia complications could be inoculated against vaccinia while everyone else is inoculated against smallpox.
A live, replicating virus, vaccinia can cause side effects, which on rare occasions can be serious and potentially life-threatening.
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