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If eaten in large quantities, the colocynth might even cause death.
In recent years colocynth has found a place in the oil industry of western Rajasthan where its cultivation serves three purposes, viz. continuous supply of seed (as cash crop) to oil industry for soap making, stabilization of shifting sand, and checking the danger of its becoming extinct due to over exploitation.
Commercial extract of colocynth may be often found in the market made with an aqueous menstruum.
Nevertheless, a century later many Victorians were taking a nightly dose of blue pill, aloes, colocynth , and castor and croton oils to purge their bowels.
Fatal cases of poisoning from overdoses of colocynth are not rare, but they represent a small percentage given its wide use.
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