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Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism , achondroplasia.
There was no history of familial dwarfism or known exposure to teratogenic drugs.
Many metals, for example, have adverse effects on plants if they are concentrated to high levels; the result is plant deformities, dwarfism , or death of the plant.
The problem, according to Martin, is that while the body size of a large species shrinks considerably in cases of island dwarfism , brain size shrinks moderately.
The scientific point was that in the past 10 years, the mutations responsible for nearly all forms of dwarfism had been identified.
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