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The Aberdeen company uses antibodies to detect haptens - tiny molecules that can signal the presence of poisonous or disease-causing substances.
It is likely that low-molecular-weight agents act as haptens , combining with human proteins in the respiratory tract to become complete immunogens.
The bound microparticle complexes are then incubated with antidetection hapten alkaline phosphatase conjugate, which binds to the detection haptens .
Supporting this is the discovery by Vojdani et al., who reported that some individuals develop allergic antibodies to haptens formed in response to MTBE binding to albumin.
Perhaps the binding of TABMs to chemical haptens produces a local increase in TGF- [Beta] at sites of chemical exposure, particularly the upper and lower respiratory tract, with neuropeptide release.
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