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Beneath the mucosa, there is a loose connective tissue layer called the submucosa .
Some of the nodules were located in the submucosa beneath areas of mucosal ulceration, but did not show communication with or disruption of the mucosa.
Between the mucosa and muscle layers lies the submucosa , which is rich in blood vessels and connective tissue.
Tumors are considered invasive if they extend through the muscularis layer and into the submucosa .
The most prominent inflammatory cells in the bronchial submucosa were lymphocytes, but their numbers changed little during exacerbations.
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