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Alternate cavities may be scarce, distant, defended, suboptimal , of unknown quality, or themselves soiled.
This gold standard may very well suffer from the problem of being a suboptimal gold standard.
Fourthly, despite efficacious treatments, the quality of care for adults with type 2 diabetes remains suboptimal .
In observational studies of handwashing, the frequency and quality of hand hygiene are consistently suboptimal .
The presence of endometriosis, tubal factor, or suboptimal sperm quality may halve the likelihood of spontaneous conception.
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