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In each of these cases, once the iatrogenic etiology of this syndrome was recognized, the patients' symptoms improved rapidly and dramatically with administration of anticholinergic medication.
If these measures are not successful, an anticholinergic drug may control the pain.
Use of the anticholinergic drug atropine during tap-water iontophoresis sometimes is helpful, but extreme caution is necessary to avoid toxicity from atropine overdose.
He thought for a minute and added, ‘So, if we improve cognition by increasing acetylcholine, it makes sense that anticholinergic drugs can make dementia a lot worse.’
Dry mouth is the most common complaint with the oral anticholinergic drugs oxybutynin and tolterodine.
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