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The process by which follicles degenerate and disappear is little understood and is termed follicular atresia .
Mary has pulmonary atresia , a condition that means the heart and the main blood vessel to the lungs have failed to develop properly.
Furthermore, they may cause premature depletion of the follicle pool by induction of follicular atresia or oocyte apoptosis and, thereby, lead to reduced fertility.
This results in atresia of the dominant follicle and re-initiation of follicular recruitment.
These structures form through a process of follicular atresia accompanied by hypertrophy of the follicular cells.
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