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He was conducting research on possible medical applications of various lysergic acid compounds derived from ergot , a fungus that develops on rye grass.
Normally the ergot is very close to the skin, but sometimes they grow out to an inch or more and can be unsightly when this hair is clipped for show purposes.
Seriously though, Rufus knew that the problems commonly blamed on rye occur when the grain is moldy and has ergot , so he was careful never to buy moldy rye.
Such molds include ergot from claviceps species, aflatoxins from Aspergillus, and trichothecenes from Fusarium and Stachybotrys.
The review included 13 controlled trials of ergot derivatives.
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