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As renal function declines, patients are likely to develop anemia because of decreased renal production of erythropoietin .
The mechanism responsible for polycythaemia is the release of the hormone erythropoietin from the kidney as a result of the shortage of oxygen there.
The marrow often has to be supported with granulocyte stimulating factor or erythropoietin .
Another important renal response to ischemia is the release of erythropoietin , which stimulates the bone marrow to increase production of red blood cells.
However, if symptoms become severe, a blood transfusion or injections of synthetic erythropoietin , a hormone normally produced by the kidneys, may help stimulate red blood cell production and ease fatigue.
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