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Tyrosine kinases associated with cyclins have also been shown to be affected by vitamin K, which can lead to cell cycle arrest and cell death.
In general, cyclins are proteins that regulate the cell cycle by combining with cyclin dependent kinases to form an enzymatic complex.
Proteasome degradation of cyclins involved in cell cycle regulation has been well documented.
It has been reported recently that regulated nuclear transport of cyclins and other proteins is required for cell cycle progression.
It is through changes in the production of cyclins during the cell cycle that the activity of the genes controlling it are themselves regulated.
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