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If cytotoxins have no ‘accomplice’ in the cell interior, chemotherapy is usually destined to fail - chemoresistance is the result.
The fer-de-lance, a pit viper from Central and South America, has in its venom several highly effective cytotoxins - chemicals that target living cells.
One cell line responded to genotoxins and the other cell line responded to cytotoxins .
Apoptosis can be induced by immune cells and cytotoxins , and by changes in homeostatic signals.
Because bioreductive drugs are activated to form highly effective cytotoxins under hypoxic conditions, they can be used to inactivate hypoxic tumor cells that are refractory to the direct cytotoxicity of hypericin-PDT.
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