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DNA bases are susceptible to hydrolytic deamination, although deamination is much less frequent in double-stranded compared to single-stranded DNA.
The spontaneous deamination of cytosine is a frequent event.
The liver, influenced by protein intake and anabolic need, makes urea from deamination of amino acids in the Krebs urea cycle.
Aspartate can also be formed by deamination of asparagine catalyzed by asparaginase.
The earliest enzymatic functions are mostly linked to amino acid catabolism: deamination , transamination, and decarboxylation.
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