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For example, physical activity increased in rats when injected with orexin , a brain chemical associated with sexual arousal.
The lateral hypothalamus contains cells that secrete a protein neurotransmitter called ‘ orexin ’ or ‘hypocretin.’
Human narcolepsy generally stems from a shortage of the neurons, which produce the excitatory neurotransmitter known both as hypocretin and orexin .
Orexin neurons are exclusively localized in the lateral hypothalamic area and project their fibers to the entire central nervous system.
Orexin A is a promising candidate to become a "sleep replacement" drug.
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