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The insular cortex is indented by a number of sulci, one of which - the central sulcus of the insula - is deeper and more prominent than the rest.
While rejecting an offer, increased brain activity was observed in the anterior insula , which is associated with negative emotions such as disgust.
The areas most affected were the superior temporal, anterior insula , and orbitofrontal cortices.
The insula relays messages between imitation and emotion regions, Iacoboni suggests.
A few seconds later, presumably as the person responded to the humor, brain regions called the insula and amygdala became active across both hemispheres of the brain.
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