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In 1911, he reported on the effect of hematoporphyrin and light on a paramecium and red blood cells and described skin reactions in mice exposed to light after hematoporphyrin administration.
Contact with protozoa, the tremendously varied group of more sophisticated single-celled microbes that includes amoeba and paramecium , has also been greatly reduced in the developed world by water and food treatment measures.
Parameciums have a permanent feeding mechanism, consisting of a funnel-shaped gullet into which food is drawn by the combined action of the cilia. They feed on small organisms such as bacteria and even other smaller protozoa.
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