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Amyloidosis and other infiltrative diseases, including sarcoidosis and haemochromatosis, can cause a restrictive syndrome.
It is often idiopathic in origin, but may be associated with multiple sclerosis, sarcoidosis , syphilis, Lyme disease, and ocular lymphoma.
The etiology of the systemic granulomatous disease sarcoidosis remains obscure.
Endoscopic procedures may be helpful in the diagnosis of disorders such as inflammatory bowel disease and sarcoidosis .
Granuloma formation in sarcoidosis may be a stereotypical response to multiple infectious and noninfectious agents.
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